DR1

Across TCGA patient cohorts, DR1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,996 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DR1-associated genes across cancer lineages are FUBP1, FAF1, and ZNHIT6. Each is linked with DR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DR1-to-partner and partner-to-DR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DR1 versus FUBP1 in BRCA, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DR1→partner) and Y-score (partner→DR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FUBP1 →	+0.420	+0.204	<.001	.003	3	6
GBM	FAF1 →	+0.454	+0.401	.003	<.001	3	6
LSCC	ZNHIT6 →	+0.405	+0.269	<.001	<.001	3	5
LUAD	ZNF644 →	+0.447	+0.193	<.001	.002	3	5
BRCA	CCDC18 →	+0.560	+0.289	.001	.001	3	5
BRCA	RPAP2 →	+0.605	+0.339	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,996 associations by consensus.

DR1 vs FUBP1 — BRCA

Explore this scatter interactively →