DQX1

Across TCGA patient cohorts, DQX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,055 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DQX1-associated proteins across cancer lineages are SPR, SPR_S103, and TMF1. Each is linked with DQX1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DQX1-to-partner and partner-to-DQX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DQX1 versus SPR in LSCC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DQX1→partner) and Y-score (partner→DQX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPR →	+0.358	+0.720	<.001	<.001	3	3
LSCC	SPR_S103 →	+0.781	+1.185	<.001	<.001	3	3
LSCC	TMF1 →	-0.182	-0.825	<.001	<.001	3	3
HNSC	RFC2 →	+0.332	+0.872	.002	<.001	3	3
HNSC	SH3KBP1 →	-0.441	-1.051	<.001	<.001	3	3
HNSC	HMCES →	+0.373	+0.733	.006	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,055 associations by consensus.

DQX1 vs SPR — LSCC

Explore this scatter interactively →