DPYSL5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DPYSL5 protein abundance is significantly associated with the RNA expression of many other genes, with 4,441 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DPYSL5-associated genes across cancer lineages are LGI4, SIGLEC17P, and S1PR5. Each is linked with DPYSL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPYSL5-to-partner and partner-to-DPYSL5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPYSL5 versus LGI4 in GBM, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPYSL5→partner) and Y-score (partner→DPYSL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMLGI4 →+1.031+0.415<.001<.00132
OVSIGLEC17P →+0.732+1.424.003.00632
GBMS1PR5 →+1.129+0.410.001.00232
OVSPNS2 →+1.448+2.243.007<.00132
OVTMEM121 →+1.260+1.367.001.00632
OVPSD →+1.264+1.711.003.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,441 associations by consensus.

DPYSL5 vs LGI4 — GBM

Per-sample scatter of DPYSL5 vs LGI4 in GBM (Pearson r = 0.33).

Explore this scatter interactively →

Exploration