DPYSL5

Across TCGA cell cohorts, DPYSL5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,682 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DPYSL5-associated GO terms across cancer lineages are Positive regulation of double-strand break repair via homologous recombination, Epigenetic regulation of gene expression, and Positive regulation of DNA repair. Each is linked with DPYSL5 in more than 14 cancer types. Because this analysis shows association rather than direction, both DPYSL5-to-partner and partner-to-DPYSL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair via homologous recombination grouped by DPYSL5-low versus DPYSL5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPYSL5→partner) and Y-score (partner→DPYSL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of double-strand break repair via homologous recombination →	+0.116	+3.779	<.001	<.001	3	15
BONE	Epigenetic regulation of gene expression →	+0.089	+3.502	<.001	<.001	3	13
SOFT_TISSUE	Positive regulation of DNA repair →	+0.066	+1.375	<.001	.002	3	13
BONE	Cell cycle phase transition →	+0.074	+2.928	<.001	<.001	3	13
BONE	Protein-DNA complex disassembly →	+0.135	+3.165	<.001	<.001	3	12
BONE	Positive regulation of DNA recombination →	+0.090	+2.780	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,682 associations by consensus.

Positive regulation of double-strand break repair via homologous recombination by DPYSL5 expression — BONE

Explore this box plot interactively →