DPYSL4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DPYSL4 protein abundance is significantly associated with the RNA expression of many other genes, with 10,510 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DPYSL4-associated genes across cancer lineages are MEIS3, PTH1R, and CERCAM. Each is linked with DPYSL4 in more than 4 cancer types. Because this analysis shows association rather than direction, both DPYSL4-to-partner and partner-to-DPYSL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPYSL4 versus MEIS3 in BRCA, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPYSL4→partner) and Y-score (partner→DPYSL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMEIS3 →+1.046+0.561.003.00635
OVPTH1R →+0.986+0.921.003<.00135
BRCACERCAM →+1.071+0.790<.001<.00135
COADHOPX →+1.149+1.313.002.00135
OVMIR100HG →+0.653+0.557.004<.00135
GBMPTPRN →+1.224+0.414<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,510 associations by consensus.

DPYSL4 vs MEIS3 — BRCA

Per-sample scatter of DPYSL4 vs MEIS3 in BRCA (Pearson r = 0.28).

Explore this scatter interactively →

Exploration