DPYSL4

Across TCGA cell cohorts, DPYSL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,070 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DPYSL4-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Proton motive force-driven ATP synthesis, and Aerobic respiration. Each is linked with DPYSL4 in more than 9 cancer types. Because this analysis shows association rather than direction, both DPYSL4-to-partner and partner-to-DPYSL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by DPYSL4-low versus DPYSL4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPYSL4→partner) and Y-score (partner→DPYSL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.106	+2.339	<.001	.002	3	10
BONE	Proton motive force-driven ATP synthesis →	+0.110	+2.741	<.001	<.001	3	9
BONE	Aerobic respiration →	+0.054	+1.712	.004	.001	3	9
BONE	Nucleosome organization →	+0.139	+2.855	<.001	<.001	3	9
BONE	Negative regulation of myoblast fusion →	+0.107	+2.441	<.001	.001	3	9
BONE	Protein-DNA complex organization →	+0.094	+2.633	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,070 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by DPYSL4 expression — BONE

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