DPYSL3

Across TCGA cell cohorts, DPYSL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,436 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DPYSL3-associated GO terms across cancer lineages are Regulation of microtubule cytoskeleton organization, Positive regulation of intracellular transport, and Regulation of cell-substrate junction organization. Each is linked with DPYSL3 in more than 9 cancer types. Because this analysis shows association rather than direction, both DPYSL3-to-partner and partner-to-DPYSL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule cytoskeleton organization grouped by DPYSL3-low versus DPYSL3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPYSL3→partner) and Y-score (partner→DPYSL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of microtubule cytoskeleton organization →	+0.045	+2.350	.005	.003	3	10
BONE	Positive regulation of intracellular transport →	+0.058	+1.696	.001	.002	3	10
SKIN	Regulation of cell-substrate junction organization →	+0.081	+2.017	.003	.004	3	9
BONE	Positive regulation of cell-substrate junction organization →	+0.163	+1.483	<.001	.001	3	9
STOMACH	Protein-containing complex disassembly →	+0.066	+2.577	.003	.002	3	9
BONE	Positive regulation of focal adhesion assembly →	+0.167	+1.293	.003	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,436 associations by consensus.

Regulation of microtubule cytoskeleton organization by DPYSL3 expression — STOMACH

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