DPYSL2

Across TCGA cell cohorts, DPYSL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,448 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DPYSL2-associated GO terms across cancer lineages are Positive regulation of pinocytosis, Positive regulation of focal adhesion assembly, and Negative regulation of calcium ion import across plasma membrane. Each is linked with DPYSL2 in more than 9 cancer types. Because this analysis shows association rather than direction, both DPYSL2-to-partner and partner-to-DPYSL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of pinocytosis grouped by DPYSL2-low versus DPYSL2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPYSL2→partner) and Y-score (partner→DPYSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of pinocytosis →	+0.126	+1.485	<.001	<.001	3	9
URINARY_TRACT	Positive regulation of focal adhesion assembly →	+0.140	+1.709	<.001	.001	3	9
LIVER	Negative regulation of calcium ion import across plasma membrane →	+0.153	+1.749	.009	.001	3	9
PANCREAS	Regulation of angiotensin-activated signaling pathway →	+0.133	+1.343	.003	.002	2	10
BREAST	Negative regulation of dendritic cell apoptotic process →	+1.526	+2.373	<.001	<.001	3	9
BREAST	Transport of virus →	+0.132	+1.436	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,448 associations by consensus.

Positive regulation of pinocytosis by DPYSL2 expression — BLOOD_Leukemia

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