Across TCGA pan-cancer cohorts, DPY19L4P2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of DPY19L4P2’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where DPY19L4P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DPY19L4P2 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
UCEC and THCA are the cancer types where DPY19L4P2 tumor–normal differential expression is most reproducible.