DPY19L4

Across TCGA cell cohorts, DPY19L4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,740 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPY19L4-associated GO terms across cancer lineages are DNA biosynthetic process, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of maintenance of sister chromatid cohesion. Each is linked with DPY19L4 in more than 15 cancer types. Because this analysis shows association rather than direction, both DPY19L4-to-partner and partner-to-DPY19L4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA biosynthetic process grouped by DPY19L4-low versus DPY19L4-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPY19L4→partner) and Y-score (partner→DPY19L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DNA biosynthetic process →	+0.066	+0.863	<.001	<.001	3	16
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.091	+1.108	<.001	<.001	3	14
OVARY	Regulation of maintenance of sister chromatid cohesion →	+0.090	+0.706	.001	.001	3	14
OVARY	Regulation of maintenance of mitotic sister chromatid cohesion →	+0.090	+0.706	.001	.001	3	14
STOMACH	Negative regulation of myoblast fusion →	+0.103	+0.710	.009	.001	3	14
OESOPHAGUS	Regulation of myoblast fusion →	+0.089	+0.495	.005	.009	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,740 associations by consensus.

DNA biosynthetic process by DPY19L4 expression — LARGE_INTESTINE

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