DPY19L4

Across TCGA cell cohorts, DPY19L4 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DPY19L4-associated genes across cancer lineages are OCM2, OR14C36, and MRGPRX2. Each is linked with DPY19L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPY19L4-to-partner and partner-to-DPY19L4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OCM2 grouped by DPY19L4-low versus DPY19L4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPY19L4→partner) and Y-score (partner→DPY19L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OCM2 →	+0.026	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR14C36 →	+0.012	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	MRGPRX2 →	+0.037	+4.093	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR4D10 →	+0.031	+4.078	<.001	.009	3	1
SKIN	ADAMTS18 →	+0.439	+3.443	.002	.009	3	1
SKIN	NEUROD1 →	+0.051	+3.799	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

OCM2 by DPY19L4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →