DPY19L2P2

Across TCGA patient cohorts, DPY19L2P2 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPY19L2P2-associated genes across cancer lineages are c-Met_pY1235, A-Raf_pS299, and TFRC. Each is linked with DPY19L2P2 in more than 2 cancer types. Because this analysis shows association rather than direction, both DPY19L2P2-to-partner and partner-to-DPY19L2P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, c-Met_pY1235 grouped by DPY19L2P2-low versus DPY19L2P2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPY19L2P2→partner) and Y-score (partner→DPY19L2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	c-Met_pY1235 →	+0.089	+2.125	<.001	.010	3	3
UCEC	A-Raf_pS299 →	-0.132	-2.459	.001	.018	3	2
UCEC	TFRC →	+0.430	+3.169	.019	.018	3	2
UCEC	TIGAR →	+0.119	+2.222	.024	.010	3	2
UCEC	ASNS →	+0.290	+1.584	.020	.034	3	2
UCEC	FoxM1 →	+0.181	+1.440	.043	.024	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

c-Met_pY1235 by DPY19L2P2 expression — UCEC

Explore this box plot interactively →