Across TCGA patient cohorts, DPY19L2P1 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPY19L2P1-associated genes across cancer lineages are Ku80, MEK1, and STAT3_pY705. Each is linked with DPY19L2P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPY19L2P1-to-partner and partner-to-DPY19L2P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPY19L2P1→partner) and Y-score (partner→DPY19L2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.191	+1.527	.017	.009	3	2
UCEC	MEK1 →	+0.345	+1.765	.005	.013	3	2
UCEC	STAT3_pY705 →	-0.366	-1.514	<.001	.015	3	2
UCEC	ATM →	-0.433	-1.247	.005	.045	3	2
UCEC	Cyclin-B1 →	+0.701	+3.000	<.001	<.001	3	2
SKCM	PKC-a →	-0.358	-1.874	.014	.047	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

DPY19L2P1 survival (RNA) · tumor vs normal (RNA) · all DPY19L2P1 data types