DPY19L2

Across TCGA cell cohorts, DPY19L2 mutation is significantly associated with the RNA expression of many other genes, with 556 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPY19L2-associated genes across cancer lineages are FAM25A, MYL2, and FZD10. Each is linked with DPY19L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPY19L2-to-partner and partner-to-DPY19L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM25A grouped by DPY19L2-low versus DPY19L2-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPY19L2→partner) and Y-score (partner→DPY19L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	FAM25A →	+0.186	+5.643	<.001	.002	3	2
BLOOD_Leukemia	MYL2 →	+0.593	+4.152	<.001	.009	3	2
BLOOD_Lymphoma	FZD10 →	+0.527	+3.954	<.001	.005	3	1
BLOOD_Lymphoma	TMEM82 →	+0.019	+4.058	<.001	.009	3	1
LARGE_INTESTINE	CBY1 →	+0.716	+3.307	<.001	.003	3	1
LARGE_INTESTINE	JOSD1 →	+0.632	+3.364	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 556 associations by consensus.

FAM25A by DPY19L2 expression — LUNG_SCLC

Explore this box plot interactively →