DPY19L1

Across TCGA patient cohorts, DPY19L1 mutation is significantly associated with the RNA expression of many other genes, with 2,443 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPY19L1-associated genes across cancer lineages are MIR6784, RPL35AP26, and MIR7155. Each is linked with DPY19L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DPY19L1-to-partner and partner-to-DPY19L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6784 grouped by DPY19L1-low versus DPY19L1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPY19L1→partner) and Y-score (partner→DPY19L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR6784 →	+0.729	+3.871	.003	.004	3	3
SKCM	RPL35AP26 →	+0.189	+3.894	.006	.004	3	3
LIHC	MIR7155 →	+0.526	+5.890	<.001	<.001	3	2
READ	TBC1D3P1-DHX40P1 →	+0.284	+5.925	<.001	.002	3	2
LIHC	ZNF736P7Y →	+0.032	+5.091	<.001	.003	3	2
LUAD	RNU1-31P →	+0.177	+4.315	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,443 associations by consensus.

MIR6784 by DPY19L1 expression — LUAD

Explore this box plot interactively →