DPT

Across TCGA cell cohorts, DPT RNA expression is significantly associated with the go_rna of many other GO terms, with 1,121 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DPT-associated GO terms across cancer lineages are Protein activation cascade, Articular cartilage development, and Positive regulation of cardiac epithelial to mesenchymal transition. Each is linked with DPT in more than 4 cancer types. Because this analysis shows association rather than direction, both DPT-to-partner and partner-to-DPT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein activation cascade grouped by DPT-low versus DPT-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPT→partner) and Y-score (partner→DPT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Protein activation cascade →	+0.316	+0.048	.004	.005	3	5
CNS	Articular cartilage development →	+0.281	+0.799	.007	.008	3	5
CNS	Positive regulation of cardiac epithelial to mesenchymal transition →	+0.068	+0.817	.008	.008	3	5
BONE	Response to monosaccharide →	+0.085	+0.783	.003	.004	3	5
BONE	Maintenance of protein location →	+0.124	+0.859	<.001	.005	3	5
LARGE_INTESTINE	One-carbon metabolic process →	-0.068	-0.095	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,121 associations by consensus.

Protein activation cascade by DPT expression — LIVER

Explore this box plot interactively →