Across TCGA pan-cancer cohorts, DPRXP1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of DPRXP1’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where DPRXP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DPRXP1 is over-expressed in tumor, although a few such as LIHC show the opposite, repressed pattern.
LUSC, STAD, and LIHC are the cancer types where DPRXP1 tumor–normal differential expression is most reproducible.