Across TCGA patient cohorts, DPRX RNA expression is significantly associated with the go_rna of many other GO terms, with 6,896 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DPRX-associated GO terms across cancer lineages are Regulation of Notch signaling pathway, Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage, and Establishment or maintenance of cell polarity. Each is linked with DPRX in more than 11 cancer types. Because this analysis shows association rather than direction, both DPRX-to-partner and partner-to-DPRX results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPRX→partner) and Y-score (partner→DPRX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of Notch signaling pathway →	+0.058	+0.160	<.001	<.001	3	12
STAD	Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage →	+0.058	+0.140	<.001	<.001	3	11
STAD	Establishment or maintenance of cell polarity →	+0.070	+0.163	<.001	<.001	3	11
STAD	Positive regulation of translation →	+0.076	+0.157	<.001	<.001	3	11
STAD	Mitochondrial membrane organization →	+0.080	+0.157	<.001	<.001	3	11
STAD	Positive regulation of intrinsic apoptotic signaling pathway →	+0.068	+0.154	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,896 associations by consensus.

Exploration

DPRX survival (RNA) · tumor vs normal (RNA) · all DPRX data types