DPPA5P1

Across TCGA pan-cancer cohorts, DPPA5P1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated DPPA5P1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher DPPA5P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DPPA5P1 expression acts as an unfavorable survival marker, although some lineages such as LGG and CHOL show a favorable association.

SKCM, LIHC, and THCA are the cancer types where DPPA5P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.613	0.800	<.001	108	view →
LIHC	DFS	Tertile	II,III,IV	0.145	0.439	.001	81	view →
THCA	DFS	Tertile	III,IV	0.357	0.762	<.001	57	view →
UCEC	OS	Tertile	IV	0.279	0.637	.011	36	view →
KIRC	DFS	Quartile	III,IV	0.311	0.510	.008	27	view →
STAD	OS	Tertile	III,IV	0.273	0.543	.014	18	view →
KICH	OS	Tertile	All	0.746	0.939	.022	15	view →
LGG	DFS	Median	All	0.890	0.788	.019	13	view →
CHOL	DFS	Tertile	II,III,IV	1.000	0.223	.047	9	view →
PAAD	DFS	Tertile	II,III,IV	0.237	0.443	.047	9	view →
ACC	DFS	Tertile	All	0.195	0.748	.003	9	view →
TGCT	DFS	Tertile	III,IV	0.340	1.000	.043	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

DPPA5P1–SKCM (OS)

Open the SKCM breakdown →