Across TCGA patient cohorts, DPPA5 mutation is significantly associated with the RNA expression of many other genes, with 338 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPPA5-associated genes across cancer lineages are BPY2DP, OTOP1, and CTU2. Each is linked with DPPA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPPA5-to-partner and partner-to-DPPA5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPPA5→partner) and Y-score (partner→DPPA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	BPY2DP →	+0.189	+5.824	<.001	.001	3	2
UCEC	OTOP1 →	+0.579	+2.661	<.001	.001	3	2
UCEC	CTU2 →	+0.619	+3.483	<.001	.002	3	2
UCEC	RN7SL140P →	+0.092	+3.707	.009	.002	3	2
UCEC	LSM10 →	+0.423	+3.483	.002	.002	3	2
UCEC	CINP →	+0.331	+3.754	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 338 associations by consensus.

Exploration

DPPA5 survival (RNA) · tumor vs normal (RNA) · all DPPA5 data types