DPPA3P3

Across TCGA pan-cancer cohorts, DPPA3P3 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated DPPA3P3 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher DPPA3P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DPPA3P3 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

LUSC, HNSC, and UCEC are the cancer types where DPPA3P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	All	0.147	0.762	.001	99	view →
HNSC	OS	Tertile	II,III,IV	0.082	0.711	<.001	99	view →
UCEC	OS	Tertile	II,III,IV	0.458	0.857	<.001	96	view →
LUAD	DFS	Tertile	IV	0.268	0.727	.010	63	view →
ESCA	OS	Tertile	III,IV	0.134	0.582	.003	60	view →
ACC	OS	Tertile	All	0.636	0.902	<.001	54	view →
OV	DFS	Tertile	All	0.427	0.151	.016	48	view →
BLCA	DFS	Tertile	All	0.176	0.521	.013	45	view →
KIRC	DFS	Tertile	IV	0.127	0.619	.008	36	view →
SKCM	DFS	Tertile	III,IV	0.362	0.662	.021	9	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

DPPA3P3–LUSC (OS)

Open the LUSC breakdown →