DPPA3P2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DPPA3P2 mutation is significantly associated with the RNA expression of many other genes, with 434 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPPA3P2-associated genes across cancer lineages are MRPL39, ONECUT1, and EXO1. Each is linked with DPPA3P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPPA3P2-to-partner and partner-to-DPPA3P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPPA3P2→partner) and Y-score (partner→DPPA3P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMRPL39 →+0.568+3.332.003.00532
UCECONECUT1 →+0.442+3.388<.001.00732
UCECEXO1 →+0.835+3.354.007.00532
UCECTIPIN →+0.760+3.343<.001.00532
UCECUHRF1 →+1.248+3.332<.001.00532
UCECCARS1 →+0.635+3.332<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 434 associations by consensus.

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