DPPA3P2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DPPA3P2 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPPA3P2-associated genes across cancer lineages are FOXO3a_pS318_S321, GAPDH, and mTOR_pS2448. Each is linked with DPPA3P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPPA3P2-to-partner and partner-to-DPPA3P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPPA3P2→partner) and Y-score (partner→DPPA3P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECFOXO3a_pS318_S321 →-0.199-3.160.003.01931
UCECGAPDH →+0.842+3.169.004.02022
UCECmTOR_pS2448 →-0.195-3.150.017.01931
UCECPKC-b-II_pS660 →-0.364-3.169.016.02031
UCECAR →-0.451-3.169.027.02031
UCECTFRC →+0.986+3.169<.001.02031
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

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