DPP9

Across TCGA pan-cancer cohorts, DPP9 Mutation is linked to patient survival in 12 of 34 cancer types, making it a survival-associated DPP9 data layer compared with 24 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher DPP9 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DPP9 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

ESCA, LUAD, and UCEC are the cancer types where DPP9 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.202	0.712	<.001	33	view →
LUAD	OS	Median	All	0.292	0.690	<.001	24	view →
UCEC	DFS	Median	All	0.975	0.619	.003	22	view →
OV	DFS	Median	II,III,IV	0.195	0.541	.015	18	view →
PCPG	OS	Median	All	0.032	0.948	<.001	12	view →
DLBC	OS	Median	All	0.054	0.842	<.001	12	view →
SKCM	OS	Median	III,IV	0.216	0.721	.001	9	view →
KIRC	OS	Median	All	0.167	0.655	.038	6	view →
PRAD	DFS	Median	All	0.617	0.886	.038	6	view →
LUSC	OS	Median	All	0.176	0.724	.018	6	view →
HNSC	DFS	Median	III,IV	1.000	0.279	.018	4	view →
LIHC	DFS	Median	All	0.217	0.556	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

DPP9–ESCA (OS)

Open the ESCA breakdown →