DPP9

Across TCGA pan-cancer cohorts, DPP9 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DPP9 data layer compared with 24 for mass-spec protein and 12 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DPP9 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DPP9 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD, PDAC, and UCEC are the cancer types where DPP9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	II,III,IV	1.000	0.704	<.001	13	view →
PDAC	DFS	Median	II,III,IV	0.267	0.458	.018	8	view →
UCEC	DFS	Median	II,III,IV	0.826	1.000	.047	2	view →
CCRCC	DFS	Median	All	0.717	0.900	.027	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DPP9–LUAD (DFS)

Open the LUAD breakdown →