DPP9

Across TCGA patient cohorts, DPP9 RNA expression is significantly associated with the mutation status of many other genes, with 13,521 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPP9-associated genes across cancer lineages are TP53, MUC17, and LAMA1. Each is linked with DPP9 in more than 4 cancer types. Because this analysis shows association rather than direction, both DPP9-to-partner and partner-to-DPP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by DPP9-low versus DPP9-high in PAAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPP9→partner) and Y-score (partner→DPP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	TP53 →	+2.355	+0.335	<.001	<.001	3	5
SARC	MUC17 →	+3.204	+0.666	.008	<.001	3	5
LUAD	LAMA1 →	+3.087	+0.294	<.001	.007	3	4
UCEC	RFX6 →	+2.202	+0.446	<.001	<.001	3	4
UCEC	MXRA5 →	+2.006	+0.378	<.001	<.001	3	4
UCEC	FLG2 →	+1.804	+0.403	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,521 associations by consensus.

TP53 by DPP9 expression — PAAD

Explore this box plot interactively →