DPP6

Across TCGA patient cohorts, DPP6 protein abundance is significantly associated with the RNA expression of many other genes, with 8,344 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DPP6-associated genes across cancer lineages are NRG2, GPIHBP1, and ABHD12. Each is linked with DPP6 in more than 2 cancer types. Because this analysis shows association rather than direction, both DPP6-to-partner and partner-to-DPP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPP6 versus NRG2 in GBM, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPP6→partner) and Y-score (partner→DPP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NRG2 →	+0.764	+0.767	<.001	<.001	3	3
PDAC	GPIHBP1 →	+0.973	+1.934	.003	.001	3	3
COAD	ABHD12 →	-0.522	-0.463	.007	.005	3	2
UCEC	SAE1 →	-0.539	-0.936	.005	<.001	3	2
UCEC	CDCA5 →	-0.977	-0.852	.002	<.001	3	2
COAD	CDC25C →	-0.870	-0.785	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,344 associations by consensus.

DPP6 vs NRG2 — GBM

Explore this scatter interactively →