DPP6

Across TCGA cell cohorts, DPP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 919 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible DPP6-associated GO terms across cancer lineages are Regulation of TORC1 signaling, Protein K48-linked ubiquitination, and Peptidyl-lysine acetylation. Each is linked with DPP6 in more than 4 cancer types. Because this analysis shows association rather than direction, both DPP6-to-partner and partner-to-DPP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of TORC1 signaling grouped by DPP6-low versus DPP6-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPP6→partner) and Y-score (partner→DPP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of TORC1 signaling →	+0.045	+2.173	.002	<.001	3	5
OVARY	Protein K48-linked ubiquitination →	+0.057	+0.124	<.001	.009	3	4
LUNG_SCLC	Peptidyl-lysine acetylation →	+0.080	+2.135	.001	<.001	3	4
CNS	Clearance of foreign intracellular DNA →	-0.411	-0.392	.003	.005	3	4
LARGE_INTESTINE	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.034	-0.024	<.001	.009	3	4
LUNG_SCLC	Nuclear RNA surveillance →	+0.084	+2.128	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 919 associations by consensus.

Regulation of TORC1 signaling by DPP6 expression — LUNG_SCLC

Explore this box plot interactively →