DPP6

Across TCGA cell cohorts, DPP6 mutation is significantly associated with the RNA expression of many other genes, with 663 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPP6-associated genes across cancer lineages are IDI2, GAGE12J, and OXNAD1. Each is linked with DPP6 in more than 2 cancer types. Because this analysis shows association rather than direction, both DPP6-to-partner and partner-to-DPP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IDI2 grouped by DPP6-low versus DPP6-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPP6→partner) and Y-score (partner→DPP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	IDI2 →	+0.018	+3.444	<.001	.003	3	3
LUNG_NSCLC_LUSC	GAGE12J →	+0.266	+4.643	<.001	.008	3	2
LARGE_INTESTINE	OXNAD1 →	+0.394	+3.743	.006	<.001	3	2
LARGE_INTESTINE	SF3B5 →	+0.622	+3.743	<.001	<.001	3	2
LUNG_NSCLC_LUAD	PRAMEF2 →	+0.009	+4.149	<.001	<.001	3	2
LUNG_NSCLC_LUAD	FOXR2 →	+0.959	+3.882	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 663 associations by consensus.

IDI2 by DPP6 expression — OVARY

Explore this box plot interactively →