Across TCGA patient cohorts, DPP4 mutation is significantly associated with the RNA expression of many other genes, with 4,860 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPP4-associated genes across cancer lineages are COX15, RMND1, and ZBTB8A. Each is linked with DPP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both DPP4-to-partner and partner-to-DPP4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPP4→partner) and Y-score (partner→DPP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COX15 →	+0.440	+1.628	<.001	<.001	3	3
UCEC	RMND1 →	+0.452	+2.042	<.001	<.001	3	3
UCEC	ZBTB8A →	+0.345	+1.981	<.001	<.001	3	3
UCEC	TRAPPC2L →	+0.438	+2.075	<.001	<.001	3	3
UCEC	PGAM1 →	+0.730	+1.513	<.001	<.001	3	3
UCEC	RRP12 →	+0.279	+1.858	.004	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,860 associations by consensus.

Exploration

DPP4 survival (RNA) · tumor vs normal (RNA) · all DPP4 data types