DPP3

Across TCGA patient cohorts, DPP3 mutation is significantly associated with the RNA expression of many other genes, with 1,746 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPP3-associated genes across cancer lineages are SPANXN2, RN7SL186P, and MIR4772. Each is linked with DPP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both DPP3-to-partner and partner-to-DPP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPANXN2 grouped by DPP3-low versus DPP3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPP3→partner) and Y-score (partner→DPP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SPANXN2 →	+0.026	+4.814	<.001	.003	3	3
BRCA	RN7SL186P →	+0.117	+5.711	<.001	.001	3	2
READ	MIR4772 →	+1.049	+5.421	<.001	.005	3	2
CESC	ZIK1P1 →	+0.030	+5.196	<.001	.001	3	2
CESC	TRIM51EP →	+0.046	+6.164	<.001	<.001	3	2
CESC	LINC02221 →	+0.066	+5.144	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,746 associations by consensus.

SPANXN2 by DPP3 expression — BLCA

Explore this box plot interactively →