DPP10-AS1

Across TCGA pan-cancer cohorts, DPP10-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of DPP10-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where DPP10-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types DPP10-AS1 is over-expressed in tumor, although a few such as COAD and KIRC show the opposite, repressed pattern.

COAD, KIRC, and LUAD are the cancer types where DPP10-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DPP10-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	−2.622	<.001	12	view →
KIRC	Male	II,III,IV	−0.482	<.001	12	view →
LUAD	Female	All	+1.035	<.001	7	view →
UCEC	All	II,III,IV	+2.058	<.001	6	view →
THCA	All	II,III,IV	+0.439	.005	4	view →
BRCA	Female	II,III,IV	+0.260	.019	4	view →
CHOL	All	All	+2.601	.001	3	view →
STAD	Male	All	−0.147	.010	3	view →
READ	Female	All	−2.711	<.001	2	view →
KICH	All	All	+0.816	.023	2	view →
LUSC	All	All	+0.532	.012	2	view →
PRAD	All	All	−0.039	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

DPP10-AS1–COAD

Open the COAD breakdown →