DPM3

Across TCGA pan-cancer cohorts, DPM3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DPM3 data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DPM3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated DPM3 expression acts as an unfavorable survival marker.

CCRCC, HNSC, and LUAD are the cancer types where DPM3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	0.652	0.952	.004	51	view →
HNSC	DFS	Tertile	III,IV	0.912	1.000	.038	2	view →
LUAD	DFS	Median	All	0.891	1.000	.014	1	view →
PDAC	OS	Median	All	0.743	0.952	.019	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DPM3–CCRCC (OS)

Open the CCRCC breakdown →