DPM3

Across TCGA patient cohorts, DPM3 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible DPM3-associated genes across cancer lineages are RN7SL134P, MIR648, and IGKV1OR-2. Each is linked with DPM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPM3-to-partner and partner-to-DPM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by DPM3-low versus DPM3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPM3→partner) and Y-score (partner→DPM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL134P →	+0.147	+4.926	.005	.002	3	2
BLCA	MIR648 →	+0.558	+4.926	<.001	.002	3	2
UCEC	IGKV1OR-2 →	+0.528	+3.715	<.001	.001	3	1
UCEC	RNU1-68P →	+0.149	+4.555	<.001	.005	3	1
BLCA	MIR3913-1 →	+0.453	+4.497	<.001	.009	3	1
BLCA	RN7SL339P →	+0.156	+4.642	.005	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

RN7SL134P by DPM3 expression — BLCA

Explore this box plot interactively →