DPM3

Across TCGA cell cohorts, DPM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,587 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPM3-associated GO terms across cancer lineages are Dolichol phosphate mannose biosynthetic process, Proton-transporting two-sector ATPase complex assembly, and Mitochondrial respiratory chain complex assembly. Each is linked with DPM3 in more than 12 cancer types. Because this analysis shows association rather than direction, both DPM3-to-partner and partner-to-DPM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dolichol phosphate mannose biosynthetic process grouped by DPM3-low versus DPM3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPM3→partner) and Y-score (partner→DPM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Dolichol phosphate mannose biosynthetic process →	+0.145	+1.282	.006	.001	3	13
KIDNEY	Proton-transporting two-sector ATPase complex assembly →	+0.105	+0.903	<.001	.001	3	10
KIDNEY	Mitochondrial respiratory chain complex assembly →	+0.075	+1.041	.002	<.001	3	10
BREAST	Mitochondrial proton-transporting ATP synthase complex assembly →	+0.114	+0.913	.001	.003	3	10
BREAST	Proton-transporting ATP synthase complex assembly →	+0.114	+0.913	.001	.003	3	10
BONE	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.103	-1.006	.003	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,587 associations by consensus.

Dolichol phosphate mannose biosynthetic process by DPM3 expression — LIVER

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