DPM3

Across TCGA cell cohorts, DPM3 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DPM3-associated genes across cancer lineages are OR10T2, TLE7, and TRPM3. Each is linked with DPM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPM3-to-partner and partner-to-DPM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10T2 grouped by DPM3-low versus DPM3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPM3→partner) and Y-score (partner→DPM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10T2 →	+0.584	+4.276	.005	.007	3	1
BLOOD_Leukemia	TLE7 →	+0.032	+4.969	<.001	.003	3	1
BLOOD_Leukemia	TRPM3 →	+0.053	+4.295	<.001	.006	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR10T2 by DPM3 expression — BLOOD_Leukemia

Explore this box plot interactively →