DPM2

Across TCGA patient cohorts, DPM2 protein abundance is significantly associated with the RNA expression of many other genes, with 302 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPM2-associated genes across cancer lineages are RPS6KA5, KLC3, and VIPR2. Each is linked with DPM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPM2-to-partner and partner-to-DPM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPM2 versus RPS6KA5 in UCEC, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPM2→partner) and Y-score (partner→DPM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS6KA5 →	+1.586	+0.342	<.001	.004	3	1
UCEC	KLC3 →	-1.626	-0.342	<.001	.004	3	1
UCEC	VIPR2 →	+0.633	+0.342	.007	.004	3	1
UCEC	NCS1 →	-1.527	-0.342	.004	.004	3	1
UCEC	CPEB3 →	+0.735	+0.341	.003	.004	3	1
UCEC	PACRG →	+1.113	+0.341	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 302 associations by consensus.

DPM2 vs RPS6KA5 — UCEC

Explore this scatter interactively →