DPM1

Across TCGA patient cohorts, DPM1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,384 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DPM1-associated genes across cancer lineages are BLOC1S2, GUCY1B1, and DPM2. Each is linked with DPM1 in more than 3 cancer types. Because this analysis shows association rather than direction, both DPM1-to-partner and partner-to-DPM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPM1 versus BLOC1S2 in COAD, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPM1→partner) and Y-score (partner→DPM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	BLOC1S2 →	-0.437	-0.203	<.001	<.001	3	4
GBM	GUCY1B1 →	-0.529	-0.263	.007	.001	3	4
OV	DPM2 →	+0.508	+0.346	<.001	<.001	3	4
LSCC	HPS6 →	-0.411	-0.191	<.001	.009	3	4
GBM	TBC1D12 →	-0.387	-0.215	.001	.001	3	4
HNSC	CLEC4A →	-0.368	-0.197	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,384 associations by consensus.

DPM1 vs BLOC1S2 — COAD

Explore this scatter interactively →