DPM1

Across TCGA cell cohorts, DPM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,243 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DPM1-associated GO terms across cancer lineages are IRE1-mediated unfolded protein response, tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation, and Somatic diversification of immunoglobulins. Each is linked with DPM1 in more than 10 cancer types. Because this analysis shows association rather than direction, both DPM1-to-partner and partner-to-DPM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IRE1-mediated unfolded protein response grouped by DPM1-low versus DPM1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPM1→partner) and Y-score (partner→DPM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IRE1-mediated unfolded protein response →	+0.140	+0.555	<.001	<.001	3	11
STOMACH	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	+0.128	+0.929	<.001	<.001	3	10
SOFT_TISSUE	Somatic diversification of immunoglobulins →	+0.060	+0.692	<.001	<.001	3	10
BLOOD_Lymphoma	Translation reinitiation →	+0.062	+0.637	<.001	.001	3	10
SOFT_TISSUE	Regulation of mitotic sister chromatid segregation →	+0.151	+0.855	<.001	<.001	3	10
SOFT_TISSUE	Protein localization to kinetochore →	+0.180	+0.847	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,243 associations by consensus.

IRE1-mediated unfolded protein response by DPM1 expression — SOFT_TISSUE

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