DPM1

Across TCGA cell cohorts, DPM1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DPM1-associated genes across cancer lineages are TRAT1, OR8B12, and POTEC. Each is linked with DPM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPM1-to-partner and partner-to-DPM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAT1 grouped by DPM1-low versus DPM1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPM1→partner) and Y-score (partner→DPM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TRAT1 →	+0.033	+4.417	<.001	.004	3	1
SOFT_TISSUE	OR8B12 →	+0.030	+4.369	<.001	.008	3	1
SOFT_TISSUE	POTEC →	+0.162	+4.635	<.001	.003	3	1
SOFT_TISSUE	OR52B6 →	+0.038	+4.635	<.001	.003	3	1
SOFT_TISSUE	OR52J3 →	+0.019	+4.369	<.001	.008	3	1
SOFT_TISSUE	GPX5 →	+0.037	+4.417	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

TRAT1 by DPM1 expression — SOFT_TISSUE

Explore this box plot interactively →