DPH7

Across TCGA patient cohorts, DPH7 mutation is significantly associated with the RNA expression of many other genes, with 1,400 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPH7-associated genes across cancer lineages are OR4D9, MIR3661, and BPTFP1. Each is linked with DPH7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPH7-to-partner and partner-to-DPH7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4D9 grouped by DPH7-low versus DPH7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPH7→partner) and Y-score (partner→DPH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR4D9 →	+0.126	+2.015	.003	.003	3	2
UCEC	MIR3661 →	+0.613	+1.938	.001	.003	3	2
HNSC	BPTFP1 →	+0.084	+5.182	.002	.007	3	2
SKCM	RNU6-542P →	+0.345	+5.039	<.001	.003	3	2
LUSC	RN7SKP213 →	+0.171	+5.337	.001	.006	3	2
UCEC	RAET1M →	+0.200	+2.015	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,400 associations by consensus.

OR4D9 by DPH7 expression — UCEC

Explore this box plot interactively →