DPH7

Across TCGA cell cohorts, DPH7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,196 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DPH7-associated GO terms across cancer lineages are Transcription pausing by RNA polymerase II, mRNA splice site recognition, and mRNA catabolic process. Each is linked with DPH7 in more than 16 cancer types. Because this analysis shows association rather than direction, both DPH7-to-partner and partner-to-DPH7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription pausing by RNA polymerase II grouped by DPH7-low versus DPH7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPH7→partner) and Y-score (partner→DPH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription pausing by RNA polymerase II →	+0.161	+0.659	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.153	+0.830	<.001	<.001	3	16
BONE	mRNA catabolic process →	+0.067	+0.803	<.001	.001	3	16
LUNG_SCLC	Spliceosomal complex assembly →	+0.122	+0.872	<.001	<.001	3	15
BONE	Nucleic acid transport →	+0.150	+0.950	<.001	<.001	3	15
BONE	RNA transport →	+0.150	+0.950	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,196 associations by consensus.

Transcription pausing by RNA polymerase II by DPH7 expression — BONE

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