DPH7

Across TCGA cell cohorts, DPH7 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPH7-associated genes across cancer lineages are BPIFB6, HTR1E, and UTF1. Each is linked with DPH7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPH7-to-partner and partner-to-DPH7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFB6 grouped by DPH7-low versus DPH7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPH7→partner) and Y-score (partner→DPH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFB6 →	+0.016	+4.022	<.001	.006	3	1
LARGE_INTESTINE	HTR1E →	+0.070	+3.345	<.001	.007	3	1
LARGE_INTESTINE	UTF1 →	+0.018	+3.632	<.001	.003	3	1
LARGE_INTESTINE	ADIPOQ →	+0.011	+3.632	<.001	.003	3	1
LARGE_INTESTINE	RIPPLY2 →	+0.494	+3.196	<.001	.007	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.010	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

BPIFB6 by DPH7 expression — LARGE_INTESTINE

Explore this box plot interactively →