DPH7

Across TCGA cell cohorts, DPH7 mutation is significantly associated with the mutation status of many other genes, with 2,525 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPH7-associated genes across cancer lineages are PLEKHA4, ZNF14, and PTGR1. Each is linked with DPH7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPH7-to-partner and partner-to-DPH7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PLEKHA4 grouped by DPH7-low versus DPH7-high in BONE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPH7→partner) and Y-score (partner→DPH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	PLEKHA4 →	+5.000	+4.437	.007	.007	1	2
BONE	ZNF14 →	+5.000	+4.437	.007	.007	1	2
BONE	PTGR1 →	+5.000	+4.437	.007	.007	1	2
BONE	KANK1 →	+5.000	+4.437	.007	.007	1	2
BONE	RSPH4A →	+5.000	+4.437	.007	.007	1	2
BONE	LEPR →	+5.000	+4.437	.007	.007	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,525 associations by consensus.

PLEKHA4 by DPH7 expression — BONE

Explore this box plot interactively →