DPH6

Across TCGA cell cohorts, DPH6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,438 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DPH6-associated GO terms across cancer lineages are Protein histidyl modification to diphthamide, Peptidyl-histidine modification, and Mononuclear cell differentiation. Each is linked with DPH6 in more than 13 cancer types. Because this analysis shows association rather than direction, both DPH6-to-partner and partner-to-DPH6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein histidyl modification to diphthamide grouped by DPH6-low versus DPH6-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPH6→partner) and Y-score (partner→DPH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein histidyl modification to diphthamide →	+0.125	+0.745	.001	.004	2	14
STOMACH	Peptidyl-histidine modification →	+0.125	+0.745	.001	.004	2	14
URINARY_TRACT	Mononuclear cell differentiation →	-0.058	-1.009	<.001	<.001	3	8
PANCREAS	DNA-templated DNA replication →	+0.076	+0.568	.003	.003	3	7
KIDNEY	Meiotic cell cycle process →	+0.038	+0.637	.009	<.001	3	7
BLOOD_Leukemia	Long-term synaptic potentiation →	-0.098	-0.444	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,438 associations by consensus.

Protein histidyl modification to diphthamide by DPH6 expression — STOMACH

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