DPH5

Across TCGA cell cohorts, DPH5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,128 significant associations in total. CNS shows the largest number of these associations.

The most reproducible DPH5-associated GO terms across cancer lineages are Glutaminyl-tRNAGln biosynthesis via transamidation, Zinc ion import into Golgi lumen, and Antigen processing and presentation of exogenous peptide antigen via MHC class Ib. Each is linked with DPH5 in more than 11 cancer types. Because this analysis shows association rather than direction, both DPH5-to-partner and partner-to-DPH5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glutaminyl-tRNAGln biosynthesis via transamidation grouped by DPH5-low versus DPH5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPH5→partner) and Y-score (partner→DPH5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Glutaminyl-tRNAGln biosynthesis via transamidation →	+0.093	+0.554	<.001	<.001	3	12
OESOPHAGUS	Zinc ion import into Golgi lumen →	+0.118	+0.793	<.001	<.001	3	11
CNS	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	-0.205	-0.603	.001	<.001	3	11
LUNG_NSCLC_LUSC	Telomeric 3' overhang formation →	+0.124	+0.990	.004	<.001	3	11
BONE	Regulation of epithelial cell apoptotic process →	-0.140	-0.716	.001	<.001	3	11
OVARY	Negative regulation of actin filament polymerization →	-0.125	-0.667	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,128 associations by consensus.

Glutaminyl-tRNAGln biosynthesis via transamidation by DPH5 expression — BONE

Explore this box plot interactively →