DPH3

Across TCGA pan-cancer cohorts, DPH3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DPH3 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DPH3 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DPH3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and UCEC show a favorable association.

CCRCC, LUAD, and UCEC are the cancer types where DPH3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	II,III,IV	0.938	0.709	.003	42	view →
LUAD	DFS	Median	All	0.899	0.946	.034	3	view →
UCEC	DFS	Quartile	All	1.000	0.833	.021	2	view →
LSCC	OS	Median	II,III,IV	0.810	1.000	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DPH3–CCRCC (OS)

Open the CCRCC breakdown →