DPH2

Across TCGA cell cohorts, DPH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,325 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DPH2-associated GO terms across cancer lineages are Ribosome biogenesis, Transcription by RNA polymerase I, and Transcription initiation at RNA polymerase I promoter. Each is linked with DPH2 in more than 15 cancer types. Because this analysis shows association rather than direction, both DPH2-to-partner and partner-to-DPH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosome biogenesis grouped by DPH2-low versus DPH2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPH2→partner) and Y-score (partner→DPH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Ribosome biogenesis →	+0.109	+0.804	<.001	<.001	3	16
SKIN	Transcription by RNA polymerase I →	+0.128	+0.927	<.001	<.001	3	16
BREAST	Transcription initiation at RNA polymerase I promoter →	+0.129	+0.821	<.001	<.001	3	16
BONE	Ribosomal large subunit biogenesis →	+0.164	+1.297	<.001	<.001	3	15
SOFT_TISSUE	DNA-templated transcription termination →	+0.100	+1.102	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	tRNA processing →	+0.064	+0.878	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,325 associations by consensus.

Ribosome biogenesis by DPH2 expression — BONE

Explore this box plot interactively →