Across TCGA pan-cancer cohorts, DPF3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DPF3 data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher DPF3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DPF3 expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

PDAC, HNSC, and GBM are the cancer types where DPF3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.687	1.000	.040	4	view →
HNSC	DFS	Median	All	0.318	0.853	.047	2	view →
GBM	OS	Quartile	All	0.654	0.307	.049	2	view →
LUAD	OS	Median	II,III,IV	0.814	0.365	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: DPF3 tumor-vs-normal RNA expression · all DPF3 data types