Across TCGA patient cohorts, DPF3 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPF3-associated genes across cancer lineages are ATM, ERK2, and mTOR_pS2448. Each is linked with DPF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPF3-to-partner and partner-to-DPF3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPF3→partner) and Y-score (partner→DPF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	ATM →	-0.586	-3.160	.018	.019	3	2
UCEC	ERK2 →	+0.152	+1.289	.013	.023	3	2
UCEC	mTOR_pS2448 →	-0.095	-1.794	.045	.024	3	2
UCEC	PCNA →	+0.211	+1.847	.002	.007	3	2
UCEC	TFRC →	+0.477	+2.700	.004	.005	3	2
UCEC	Bak →	+0.167	+1.700	.037	.040	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

DPF3 survival (RNA) · tumor vs normal (RNA) · all DPF3 data types